L-Glutathione (GSH)

Research-grade Glutathione (GSH tripeptide) is the most abundant non-protein thiol in mammalian cells. This reduced γ-linked tripeptide (L-γ-glutamyl-L-cysteinyl-glycine) is a well-characterized molecule that has been extensively studied in the context of redox biology. As documented in the peer-reviewed literature, GSH serves as a cofactor for glutathione peroxidase (GPx) and glutathione S-transferase (GST), and plays a central role in cellular redox homeostasis (ncbi.nlm.nih.gov, pmc.ncbi.nlm.nih.gov). This research-grade lyophilized powder is produced under strict quality standards and includes full analytical documentation, making it suitable for in-vitro oxidative stress, redox signaling, and detoxification pathway research. Research-grade Glutathione (GSH tripeptide)

Key Scientific Specifications

• Ultra-high-purity reduced Glutathione (≥ 99.5% by HPLC, pharmaceutical grade)
• Verified structure: γ-Glu-Cys-Gly (reduced thiol form, >98% GSH vs. GSSG)
• Lyophilized powder for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, Ellman’s assay (free thiol), mass spectrometry, and endotoxin testing
• Manufactured in GMP-aligned, ISO-compliant facilities
• Suitable for ROS scavenging, GPx/GST cofactor, and redox balance in-vitro studies

Research-Referenced Attributes (Based on published scientific literature; not intended as therapeutic claims. For laboratory research use only.)

• Extensively studied endogenous antioxidant molecule: reacts with ·OH, ONOO⁻, H₂O₂ in biochemical assay contexts (frontiersin.org)
• The GSH/GSSG ratio is a widely used marker of cellular redox state in laboratory models — studied in relation to protein folding, DNA synthesis, and immune cell function in-vitro
• Serves as an essential cofactor for the glyoxalase system (methylglyoxal detoxification pathways) and is investigated in heavy-metal chelation research models
• Relevant to in-vitro research applications in redox biology, oncology, cell models, neuroscience, and environmental toxicology (mdpi.com)

Why Researchers Choose Nationwide Peptides Glutathione

• High-purity reduced GSH with the highest documented free-thiol content and lowest GSSG contamination among research suppliers
• Transparent analytical data (HPLC >99.5%, Ellman’s assay >98% reduced)
• Trusted by redox biology and biochemistry laboratories
• Competitive research pricing with bulk options available

For Research Use Only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any condition.